Opportunity Information: Apply for CDC RFA PS20 2010

The CDC funding opportunity titled "Integrated HIV Programs for Health Departments to Support Ending the HIV Epidemic in the United States" (Funding Opportunity Number CDC RFA PS20-2010) is a fiscal year 2020 cooperative agreement designed to help health departments build and run comprehensive HIV programs that directly support the federal "Ending the HIV Epidemic" (EHE) initiative. The central aim is to accelerate progress toward a national target of reducing new HIV infections by 75 percent within five years and by 90 percent by 2030. The NOFO is framed around the idea that recent advances in HIV prevention and treatment make these reductions achievable, but only if jurisdictions strengthen data-driven, integrated public health work and expand the reach and effectiveness of proven prevention and care strategies.

A key feature of this opportunity is its emphasis on coordination and complementarity with other major federal HIV and primary care efforts, especially the HRSA Ryan White HIV/AIDS Program and HRSA Bureau of Primary Care Health Center Programs, along with other HHS-supported programs. Rather than duplicating what those systems do, the CDC funding is intended to help health departments use surveillance, prevention infrastructure, and public health tools to more efficiently identify needs, close gaps, and move people along the prevention and care continua. In practical terms, this means leveraging "powerful data, tools and resources" to better target interventions, improve linkage to services, and reduce community-level transmission.

The NOFO focuses the initial national push on the jurisdictions most heavily impacted by HIV. The EHE strategy described in the announcement prioritizes 50 key jurisdictions (48 counties plus Washington, DC and San Juan, Puerto Rico) as well as seven states, reflecting a geographic concentration where intensified effort is expected to yield the largest and fastest reductions in new infections. The program is explicitly designed to support locally tailored work in these places, with CDC noting that public health responses must fit local circumstances and encouraging applicants to propose "disruptively innovative" activities that match their jurisdiction's realities, barriers, and opportunities.

This funding builds on CDC's earlier integrated HIV surveillance and prevention investments, specifically referencing PS18-1802. The NOFO positions EHE funding as a way to strategically advance HIV prevention by initiating new activities or expanding existing ones, rather than starting from scratch. CDC describes the strategies in the NOFO as discrete areas of activity grounded in the best available scientific evidence and program experience, selected because they are expected to most rapidly accelerate reductions in new HIV infections when implemented well and at sufficient scale.

Structurally, the opportunity is divided into multiple components, with Component A identified as the required core of the program. Applicants must apply for Component A, and applications for Components B and C are only considered if Component A is included. In other words, Component A forms the foundation of the award, while Components B and C are optional additions that depend on submitting a qualifying Component A application. Applicants are instructed to submit a single application package that addresses the requirements for each component they are seeking.

Funding amounts are not presented as a single fixed cap in the source information (the award ceiling is listed as 0, which typically signals that awards vary by formula rather than a single maximum). Instead, funding levels are determined by formulas that include a base amount and adjustments based on HIV disease prevalence, the number of counties within a health department's jurisdiction (when applicable), and program performance in later years. This approach signals that jurisdictions with higher burden and broader administrative scope may receive more resources, and that continued funding may increasingly reflect measurable results and performance over time.

Eligibility is limited to governmental public health entities: state governments, county governments, and city or township governments. The administering agency is the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, specifically within NCHHSTP. The opportunity category is discretionary, the funding instrument is a cooperative agreement (implying substantial federal involvement and ongoing programmatic collaboration rather than a hands-off grant), and the activity category is health. The CFDA number listed is 93.940.

Administratively, the opportunity was created on January 23, 2020, with an original application closing date of March 25, 2020. Applications were required to be submitted electronically by 11:59 p.m. Eastern Time on the due date. The CDC anticipated making 48 awards, indicating broad but still limited coverage aimed at the highest-need jurisdictions and aligned with the EHE focus areas.

Overall, this NOFO is meant to help health departments intensify and modernize HIV prevention and surveillance-driven public health practice in a way that is tightly aligned with national EHE goals. It encourages jurisdictions to use data to target interventions, coordinate with clinical care and support systems like Ryan White and health centers, and implement evidence-based strategies at a pace and scale sufficient to drive down new HIV infections quickly, while still leaving room for innovative approaches that reflect the on-the-ground realities of each community.

  • The Department of Health and Human Services, Centers for Disease Control - NCHHSTP in the health sector is offering a public funding opportunity titled "Integrated HIV Programs for Health Departments to Support Ending the HIV Epidemic in the United States" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.940.
  • This funding opportunity was created on Jan 23, 2020.
  • Applicants must submit their applications by Mar 25, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 48 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments.
Apply for CDC RFA PS20 2010

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Frequently Asked Questions (FAQs)

What is the title of this CDC funding opportunity?

The funding opportunity is titled "Integrated HIV Programs for Health Departments to Support Ending the HIV Epidemic in the United States."

What is the Funding Opportunity Number (NOFO/FON)?

The Funding Opportunity Number is CDC RFA PS20-2010.

What type of funding mechanism is this?

This is a cooperative agreement, which typically means CDC expects substantial involvement and ongoing programmatic collaboration compared with a more hands-off grant.

Which federal agency administers this opportunity?

The administering agency is the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), within NCHHSTP.

What is the CFDA number associated with this program?

The CFDA number listed for this opportunity is 93.940.

What is the overall purpose of this cooperative agreement?

The purpose is to help health departments build and run comprehensive, integrated HIV programs that directly support the federal Ending the HIV Epidemic (EHE) initiative, using surveillance and prevention infrastructure to strengthen data-driven public health work and expand proven HIV prevention and care strategies.

How does this opportunity connect to the Ending the HIV Epidemic (EHE) initiative?

The NOFO is designed to accelerate progress toward EHE goals by supporting health departments in using integrated, data-driven approaches to reduce community-level transmission and improve movement along HIV prevention and care continua.

What national impact targets are referenced in the announcement?

The NOFO references national targets of reducing new HIV infections by 75 percent within five years and by 90 percent by 2030.

Who is eligible to apply?

Eligibility is limited to governmental public health entities: state governments, county governments, and city or township governments.

Is this opportunity open to nonprofits, universities, hospitals, or individuals?

Based on the information provided, eligibility is limited to state, county, and city or township governments (governmental public health entities). No other applicant types are listed as eligible in the provided details.

What is the focus of the initial national push under this opportunity?

The initial EHE strategy prioritizes the jurisdictions most heavily impacted by HIV: 50 key jurisdictions (48 counties plus Washington, DC and San Juan, Puerto Rico) and seven states, where intensified effort is expected to yield faster reductions in new infections.

Does the NOFO require activities to be tailored locally?

Yes. The program is designed to support locally tailored work, emphasizing that responses must fit local circumstances and encouraging applicants to propose "disruptively innovative" activities aligned with their jurisdiction's realities, barriers, and opportunities.

How is this NOFO intended to relate to HRSA programs like Ryan White and Health Centers?

A core feature is coordination and complementarity with other federal HIV and primary care efforts, especially the HRSA Ryan White HIV/AIDS Program and HRSA Bureau of Primary Care Health Center Programs. The CDC funding is intended to help health departments use surveillance and public health tools to identify needs, close gaps, and improve linkage to services without duplicating what those systems do.

What kinds of approaches does the NOFO emphasize?

The NOFO emphasizes data-driven, integrated public health work that leverages surveillance, prevention infrastructure, and other public health tools to better target interventions, improve linkage to services, and reduce community-level transmission.

Does the NOFO build on any prior CDC investments?

Yes. The funding builds on CDC's earlier integrated HIV surveillance and prevention investments and specifically references PS18-1802.

Is the program meant to start entirely new work, or expand existing work?

The NOFO positions EHE funding as a way to strategically advance HIV prevention by initiating new activities or expanding existing ones, rather than starting from scratch.

How is the opportunity structured (components)?

The opportunity is divided into multiple components. Component A is identified as the required core of the program.

Is Component A required to apply?

Yes. Applicants must apply for Component A.

Can an applicant apply for Components B and C without Component A?

No. Applications for Components B and C are only considered if Component A is included.

Do applicants submit separate applications for each component?

No. Applicants are instructed to submit a single application package that addresses the requirements for each component they are seeking.

Is there a fixed maximum award amount (ceiling)?

No single fixed cap is presented in the provided information. The award ceiling is listed as 0, which commonly indicates awards vary rather than having one stated maximum.

How are funding amounts determined?

Funding levels are determined by formulas that include a base amount and adjustments based on HIV disease prevalence, the number of counties within a health department's jurisdiction (when applicable), and program performance in later years.

Does performance affect future-year funding under this award?

Yes. The provided information indicates that program performance in later years is part of the funding formula, signaling that continued funding may increasingly reflect measurable results and performance over time.

What is the opportunity category and activity category?

The opportunity category is discretionary, and the activity category is health.

When was this opportunity created?

The opportunity was created on January 23, 2020.

What was the original application due date and time?

The original application closing date was March 25, 2020, and applications were required to be submitted electronically by 11:59 p.m. Eastern Time on the due date.

How many awards did CDC anticipate making?

CDC anticipated making 48 awards.

What is the central idea behind the NOFO's strategy?

The NOFO is framed around the idea that advances in HIV prevention and treatment make major reductions in new infections achievable, but only if jurisdictions strengthen integrated, surveillance-driven public health work and implement proven prevention and care strategies at sufficient pace and scale.

What does "integrated HIV programs" mean in the context provided?

In the context provided, it refers to health departments building comprehensive HIV programs that connect surveillance, prevention infrastructure, and public health tools to better target interventions, improve linkage to services, and support prevention and care continua, while coordinating with clinical care and support systems.

Does the NOFO encourage innovative approaches?

Yes. The NOFO encourages applicants to propose "disruptively innovative" activities that align with local circumstances and are expected to accelerate reductions in new HIV infections.

Why does the NOFO emphasize coordination rather than duplication with other programs?

The provided information explains that CDC funding is intended to complement major federal HIV and primary care efforts (not duplicate them) by using surveillance and public health infrastructure to identify needs, close gaps, and improve movement along service continua more efficiently.

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