Opportunity Information: Apply for RFA HL 19 019

The Summer Institute for Research Education in Biostatistics (R25 - Clinical Trials Not Allowed) is a National Institutes of Health (NIH) research education grant opportunity issued by the National Heart, Lung, and Blood Institute (NHLBI) under the NIH Research Education Program (R25). It is designed to strengthen the national biomedical, behavioral, and clinical research workforce by supporting education-focused programs that build practical research skills, specifically in biostatistics. The central idea is not to fund traditional hypothesis-driven research projects, but to fund structured educational experiences that help trainees, early-career researchers, or other targeted learner groups gain competencies that make them more effective contributors to health research.

This funding opportunity (RFA-HL-19-019) emphasizes creative educational activities, with the primary focus placed on "Courses for Skills Development." In practice, that means the supported program is expected to deliver organized instruction and hands-on learning in biostatistical concepts and methods that are directly relevant to biomedical and clinical research. A typical summer institute model would include intensive short-course training, workshops, problem-based learning, and mentored exercises using real or realistic datasets. The goal is workforce development: improving participants ability to design studies, choose appropriate statistical approaches, analyze and interpret data responsibly, and communicate findings clearly in the context of biomedical science, including heart, lung, blood, and sleep-related research areas aligned with NHLBI's mission.

The opportunity is categorized as a discretionary grant and uses the R25 funding instrument, which is specifically aimed at research education rather than research itself. As indicated by "Clinical Trials Not Allowed," applicants must ensure that proposed activities do not include conducting clinical trials as part of the grant. Educational use of clinical trial data for teaching purposes may be possible depending on the terms of the FOA and NIH policy, but the program cannot prospectively assign human participants to interventions to evaluate health outcomes. Programs should therefore be structured around instruction, secondary data analysis, simulations, methodological training, and other educational formats that do not cross into clinical trial conduct.

Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and additional eligible organizations as described in the FOA's detailed eligibility language. In general, the intent is to allow universities and similar education-capable organizations to propose and run a summer training institute with sufficient infrastructure, qualified faculty, and administrative support to recruit participants, deliver curriculum, and evaluate educational outcomes. The administering federal agency is the U.S. Department of Health and Human Services, National Institutes of Health, and the funding is associated with CFDA numbers 93.233, 93.837, 93.838, and 93.839, which reflect NIH and NHLBI programmatic areas.

From a funding standpoint, the opportunity listed an award ceiling of $240,000 and anticipated approximately 6 awards. That combination suggests a moderately sized cohort-based training program rather than a large national center, with budgets likely supporting faculty time, curriculum development and delivery, trainee-related expenses where allowable, evaluation activities, and program administration. The funding level is consistent with an intensive summer institute format that can bring together a group of participants for a defined period, provide high-quality instruction, and potentially incorporate follow-up activities such as continued mentorship, remote modules, or alumni networking to reinforce skills and promote longer-term career development.

In summary, this NHLBI R25 opportunity supports the development and delivery of a summer biostatistics education program focused on skills development, intended to broaden and strengthen the biomedical research workforce. It funds education and training infrastructure and programming, not clinical trials or independent research projects, and it targets institutions capable of delivering high-impact, well-evaluated short-course training that aligns with NIH and NHLBI workforce and research mission needs.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Summer Institute for Research Education in Biostatistics (R25 - Clinical Trials Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.837, 93.838, 93.839.
  • This funding opportunity was created on Apr 18, 2018.
  • Applicants must submit their applications by Jun 28, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $240,000.00 in funding.
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA HL 19 019

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Frequently Asked Questions (FAQs)

What is the Summer Institute for Research Education in Biostatistics (R25 - Clinical Trials Not Allowed)?

This is a National Institutes of Health (NIH) research education grant opportunity issued by the National Heart, Lung, and Blood Institute (NHLBI) under the NIH Research Education Program (R25). It supports structured, education-focused programs (often in a summer institute format) that build practical research skills in biostatistics for biomedical, behavioral, and clinical research.

What is the main purpose of this funding opportunity?

The purpose is workforce development: strengthening the national biomedical, behavioral, and clinical research workforce by funding organized educational experiences that help participants gain real, usable competencies in biostatistics. The intent is to make trainees and other learner groups more effective contributors to health research.

Is this grant meant to fund traditional research projects?

No. The central idea is not to fund traditional hypothesis-driven research projects. Instead, it funds research education programming: curriculum, instruction, mentored learning exercises, and other training activities that build practical skills in biostatistical methods relevant to biomedical and clinical research.

Which NIH institute is sponsoring and administering this opportunity?

The opportunity is issued by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services.

What is the FOA identifier for this opportunity?

The funding opportunity announcement (FOA) referenced is RFA-HL-19-019.

What funding mechanism is used?

This opportunity uses the R25 funding instrument, which is specifically intended for research education rather than conducting research. It is described as a discretionary grant under NIH’s Research Education Program (R25).

What kinds of educational activities are emphasized?

The FOA emphasizes creative educational activities, with the primary focus on "Courses for Skills Development." In practice, that means organized instruction and hands-on learning in biostatistical concepts and methods that are directly relevant to biomedical and clinical research.

What might a typical summer institute supported by this grant look like?

Based on the description provided, a typical model may include intensive short-course training, workshops, problem-based learning, and mentored exercises using real or realistic datasets. Programs may also include methodological training, simulations, and structured opportunities to practice analyzing, interpreting, and communicating results.

What skills is the program expected to strengthen for participants?

The goal is to improve participants’ ability to design studies, choose appropriate statistical approaches, analyze and interpret data responsibly, and communicate findings clearly in a biomedical research context. The program is intended to build competencies that translate into stronger contributions to health research.

How does the NHLBI mission relate to the program content?

The training is described as relevant to biomedical science areas aligned with NHLBI’s mission, including heart, lung, blood, and sleep-related research. Programs are expected to be applicable to research topics within these areas while focusing on broadly useful biostatistics skills.

Are clinical trials allowed under this grant?

No. The opportunity is explicitly labeled "Clinical Trials Not Allowed." Proposed activities must not include conducting clinical trials as part of the grant.

What does "Clinical Trials Not Allowed" mean in practical terms?

It means the program cannot prospectively assign human participants to interventions to evaluate health outcomes. The supported activities should remain educational in nature and should not cross into clinical trial conduct.

Can clinical trial data be used for teaching purposes?

The description indicates that educational use of clinical trial data for teaching purposes may be possible depending on the FOA terms and NIH policy. However, the program itself cannot include conducting a clinical trial.

What types of activities are generally appropriate given the clinical trials restriction?

The opportunity description suggests instruction, secondary data analysis, simulations, and methodological training as examples of educational formats that fit the "Clinical Trials Not Allowed" requirement.

Who is eligible to apply?

Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and additional eligible organizations as described in the FOA’s detailed eligibility language. The overall intent is to allow universities and similar education-capable organizations to propose and run the summer institute.

What organizational capabilities are implied for competitive applicants?

The description indicates applicants should have sufficient infrastructure, qualified faculty, and administrative support to recruit participants, deliver the curriculum, and evaluate educational outcomes.

How many awards are anticipated?

The opportunity anticipated approximately 6 awards.

What is the maximum award amount (award ceiling)?

The listed award ceiling is $240,000.

What does the funding level suggest about the size or scope of the program?

The combination of a $240,000 award ceiling and an anticipated ~6 awards suggests a moderately sized, cohort-based training program (such as an intensive summer institute) rather than a large national center.

What kinds of costs might the budget support?

The description indicates budgets are likely to support items such as faculty time, curriculum development and delivery, trainee-related expenses where allowable, evaluation activities, and program administration.

Are follow-up activities after the summer institute allowed or expected?

The description notes that programs could potentially incorporate follow-up activities to reinforce skills and promote longer-term career development, such as continued mentorship, remote modules, or alumni networking. Specific expectations would depend on how the applicant proposes the program within the FOA framework.

What are the CFDA numbers associated with this opportunity?

The funding is associated with CFDA numbers 93.233, 93.837, 93.838, and 93.839, reflecting NIH and NHLBI programmatic areas.

What is the overall takeaway for applicants?

This NHLBI R25 opportunity supports the development and delivery of a summer biostatistics education program focused on skills development. It funds education and training infrastructure and programming (not independent research projects or clinical trials) and is aimed at institutions that can deliver high-impact, well-evaluated training aligned with NIH and NHLBI workforce goals.

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